69. Chao, T.-H.; Lam, T.; Vong, B. G.; Traves, P. G.; Hortelano, S.; Chowdhury, C.; Bahjat, F. R.; Lloyd, G. K.; Moldawer, L. L.; Bosca, L.; Palladino, M. A.; Theodorakis, E. A. "A New Family of Synthetic Diterpenes that Regulates Cytokine Synthesis by Inhibiting IkB Phosphorylation" ChemBioChem 2005, 6, 133-144. PDF file

70. Haidekker, M. A.; Akers, W.; Lichlyter, D.; Brady, T. P.; Theodorakis, E. A. "Sensing of Flow and Shear Stress Using Molecular Rotors" Sensor Lett. 2005, 3, 42-48. PDF file

71. Lee, H.; Lee, K.; Jung, J.-K.; Cho, J.; Theodorakis, E. A. "Synthesis and Evaluation of 6-hydroxy-7-methoxy-4-chromanone- and chroman-2-carboxamides as antioxidants" Bioorg. & Med. Chem. Lett. 2005, 15, 2745-2748. PDF file

72. Peyssonnaux, C.; Datta, V.; Cramer, T.; Doedens, A.; Theodorakis, E. Gallo, R.; Hurtado-Ziola, N.; Nizet, V.; Johnson, R. S. "HIF-1a expression regulates the bactericidal capacity of phagocytes" J. Clin. Invest. 2005, 115, 1806-1815. PDF file
*See commentaries on this work: PDF comment1 PDF comment2

73. Rivas, F.; Ghosh, S.; Theodorakis, E. A. "Synthetic Studies Towards the Zoanthamine Alkaloids: Synthesis of the Fully Functionalized BC Ring Motif" Tetrahedron Lett. 2005, 46, 5281-5284. PDF file

74. Brady, T. P.; Kim, S. H.; Wen, K.; Kim, C.; Theodorakis, E. A. "Norrisolide: Total Synthesis and Related Studies" Chemistry Eur. J. 2005, 11, 7175-7190. PDF file Supplement PDF

75. Haidekker, M. A.; Brady, T. P.; Lichlyter, D.; Theodorakis, E. A. "Effects of Solvent Polarity and Solvent Viscosity on the Fluorescent Properties of Molecular Rotors and Related Probes" Bioorg. Chem. 2005, 33, 415-425. PDF file

76. Haidekker, M. A.; Brady, T. P.; Lichlyter, D.; Theodorakis, E. A. “A Ratiometric Fluorescent Viscosity Sensor” J. Am. Chem. Soc. 2006, 128, 398-399. PDF file Supplement PDF
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**and by the Am. Chem. Soc. in Heart Cut Feb. 20, 2006 PDF file

77. Alexander, M. D.; Burkart, M. D.; Leonard, M. S.; Portonovo, P.; Liang, B.; Ding, X.; Joullie, M. M.; Gulledge, B. M.; Aggen, J. B.; Chamberlin, R. A.; Sandler, J.; Fenical, W.; Cui, J.; Gharpure, S. J.; Polosukhin, A.; Zhang, H.-R.; Evans, P. A.; Richardson, A. D.; Harper, M. K.; Ireland, C. M.; Vong, B. G.; Brady, T. P.; Theodorakis, E. A.; La Clair, J. J. “A Central Strategy for Converting Natural Products into Fluorescent Probes” ChemBioChem 2006, 7, 409-416. PDF file Supplement PDF

78. Guizzunti, G.; Brady, T. P.; Malhotra, V. Theodorakis E. A. “Chemical Analysis of Norrisolide-Induced Golgi Vesiculation” J. Am. Chem. Soc. 2006, 128, 4190-4191. PDF file Supplement PDF

79. Sorensen, E. J.; Theodorakis, E. A. “Nature-Inspired Approaches to Chemical Synthesis” Tetrahedron 2006, 62, 5169 (Editorial preface). PDF file

80. Vong, B. G.; Theodorakis, E. A. “Metal-Substituted Benzo-1,4-quinones” in Science of Synthesis, Ed.: A. G. Griesbeck, Houben-Weyl Methods in Molecular Transformations, Georg Thieme Verlag, Stuttgart, NY, 2006, 28, 13-29 (Book Chapter). PDF file

81. Kim, S. H.; Theodorakis, E. A. “Chalcogen-Substituted Benzo-1,4-quinones” in Science of Synthesis, Ed.: A. G. Griesbeck, Houben-Weyl Methods in Molecular Transformations, Georg Thieme Verlag, Stuttgart, NY, 2006, 28, 53-69 (Book chapter). PDF file

82. Lee, H.; Theodorakis, E. A. “Nitrogen- and Phosphorus-Substituted Benzo-1,4-quinones” in Science of Synthesis, Ed.: A. G. Griesbeck, Houben-Weyl Methods in Molecular Transformations, Georg Thieme Verlag, Stuttgart, NY, 2006, 28, 71-86 (Book chapter). PDF file

83. Haidekker, M. A.; Akers, W. J.; Fischer, D.; Theodorakis, E. A. “Optical Fiber-Based Fluorescent Viscosity Sensor” Optics Lett. 2006, 31, 2529-2531. PDF file

84. Guizzunti, G.; Brady, T. P.; Malhotra, V.; Theodorakis, E. A. “Trifunctional Norrisolide Probes for the Study of Golgi Vesiculation” Bioorg. & Med. Chem. Lett. 2007, 17, 320-325. PDF file

85. Batova, A.; Lam, Thanh, Wascholowski, V.; Yu, A. L.; Giannis, A.; Theodorakis, E. A. “Synthesis and Evaluation of Caged Garcinia Xanthones” Org. & Biomol. Chem. 2007, 5, 494-500. PDF file Supplement PDF

86. Fischer, D.; Theodorakis, E. A.; Haidekker, M. A. “Synthesis and Use of an In-Solution Ratiometric Fluorescent Viscosity Sensor” Nature Protocols 2007, 2, 227-236. PDF file

87. Traves, P. G.; Hortelano, S.; Zeini, M.; Chao, T.-H.; Lam, T.; Neuteboom, S. T.; Theodorakis, E. A.; Palladino, M. A.; Castrillo, A.; Bosca, L. “Selective Activation of Liver X Receptors by Acanthoic Acid-related Diterpenes” Mol. Pharmacol. 2007, 71, 1545-1553. PDF file

88. Haidekker, M. A.; Theodorakis, E. A. “Molecular Rotors; Fluorescent Biosensors for Viscosity and Flow” Org. & Biomol. Chem. 2007, 5, 1669-1678. PDF file Cover PDF

89. Fischer, D.; Theodorakis, E. A. “Studies on the Synthesis of Schisandraceae Natural Products: Exploring A Cyclopropylcarbinol Ring Expansion Strategy” Eur. J. Org. Chem. 2007, 4193-4196. PDF file Supplement PDF

90. Nipper, M. E.; Majd, S.; Mayer, M.; Lee, J.; Theodorakis, E. A.; Haidekker, M. A. “Characterization of Changes in the Viscosity of Lipid Membranes with the Molecular Rotor FCVJ” Biochim. Biophys. Acta Biomembranes 2008, 1778, 1148-1153. PDF file

91. Diaz-Rodriguez, A.; Fernandez, S.; Sanghvi, Y. S.; Theodorakis, E. A.; Gotor, V.; Ferrero, M. “Synthesis of 2’,3’-cyclohexene Bicyclic Nucleoside Analogues as Antiviral Compounds” Nucleic Acids Symp. Ser. 2008, 52, 99-100. PDF file

92. Diaz-Rodriguez, A.; Sanghvi, Y. S.; Fernandez, S.; Schinazi, R. F.; Theodorakis, E. A.; Ferrero, M.; Gotor, V.; “Synthesis and anti-HIV activity of conformationally restricted bicyclic hexahydroisobenzofuran nucleoside analogs” Org. Biomol. Chem. 2009, 7, 1415-1423. PDF file

93. Pongkittiphan, V.; Theodorakis, E. A.; Chavasiri, W. “Hexachloroethane: a highly efficient reagent for the synthesis of chlorosilanes from hydrosilanes” Tetrahedron Lett. 2009, 50, 5080-5082.  PDF file

94. Chantarasriwong, O.; Cho, W. C.; Batova, A.; Chavasiri, W.; Moore, C.; Rheingold, A. L.; Theodorakis, E. A. “Evaluation of the pharmacophoric motif of the caged Garcinia xanthones” Org. & Biomol. Chem. 2009, 7, 4886-4894. PDF File Supplement PDF


 
   
     
 
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