95.  Sutharsan, J.; Lichlyter, D.; Wright, N. E.; Dakanali, M.; Haidekker, M. A.; Theodorakis, E. A. “Molecular rotors: Synthesis and evaluation as viscosity sensors” Tetrahedron 2010, 66, 2582-2588. PDF File Supplement PDF

96. Sutharsan J.; Dakanali, M.; Capule, C. C.; Haidekker, M. A.; Yang, J.; Theodorakis, E. A. “Rational design of amyloid binding agents based on the molecular rotor motif” ChemMedChem 2010, 5, 56-60. PDF File Supplement PDF

97. Guizzunti, G.; Brady, T. P.; Fischer, D.; Malhotra, V.; Theodorakis, E. A. “Chemical biology studies on norrisolide” Bioorg. & Med. Chem. 2010, 18, 2115-2122.  PDF File Supplement PDF

98. Mustafic, A.; Huang, H.-M.; Theodorakis, E. A. Haidekker, M. A. “Imaging of flow patterns with fluorescent molecular rotors” J. Fluoresc. 2010, 20, 1087-1098. PDF File

99. Haidekker, M. A.; Nipper, M.; Mustafic, A.; Lichlyter, D.; Dakanali, M.; Theodorakis, E. A. “Dyes with Segmental Mobility: Molecular Rotors” Advanced Fluorescence Reporters in Chemistry and Biology I: Fundamentals and Molecular Design Demchenko A. P. (ed.), Springer Ser. Fluoresc. 2010, 8, 267-308. PDF File

100.  Chantarasriwong, O.; Batova, A.; Chavasiri, W.; Theodorakis, E. A. “Chemistry and Biology of Caged Garcinia Xanthones” Chem. Eur. J. 2010, 16, 9944-9962. PDF File

101.  Xu, J.; Caro-Diaz, E. J. E.; Theodorakis, E. A. “Enantioselective Formal Synthesis of ()-Englerin A via a Rh-catalyzed [4+3] Cycloaddition Reaction” Org. Lett. 2010, 12, 3708-3711. PDF File Supplement PDF

102. Haidekker, M. A.; Theodorakis, E. A. “Environment-sensitive behavior of fluorescent molecular rotors” J. Biol. Engineering 2010, 4, 11. PDF File

103.  Batova, A.; Altomare, D.; Chantarasriwong, O.; Ohlsen, K. L.; Creek, K. E.; Lin, Y.-C.; Messersmith, A.; Yu, A. L. Yu, J.; Theodorakis, E. A. “The synthetic caged Garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activities” Mol. Cancer Ther. 2010, 9, 2869-2878. PDF File

104.  Nipper, M. E.; Dakanali, M.; Theodorakis, E. A.; Haidekker, M. A. “Detection of liposome membrane viscosity perturbations with ratiometric molecular rotors” Biochimie 2011, 93, 988-994. PDF File

105.  Xu, J.; Trzoss, L.; Chang, W. K.; Theodorakis, E. A. “Enantioselective Total Synthesis of (–)-Jiadifenolide” Angew. Chem. Int. Ed. 2011, 50, 3672-3676. PDF File Supplement PDF

106.  Ling, T.; Xu, J.; Smith, R.; Ali, A.; Cantrell, C. L. Theodorakis, E. A. “Synthesis of (–)-callicarpenal, a potent arthropod repellent” Tetrahedron 2011, 67, 3023-3029. PDF File Supplement PDF

107.  Yoon, H.-J.; Dakanali, M.; Lichlyter, D.; Chang, W. M.; Nguyen, K. A.; Nipper, M. E. Haidekker, M. A.; Theodorakis, E. A. “Synthesis and evaluation of self-calibrating ratiometric viscosity sensors” Org. Biomol. Chem. 2011, 9, 3530-3540. PDF File Supplement PDF

108. Chang, W. M.; Dakanali, M.; Capule, C. C.; Sigurdson, C. J.; Yang, J.; Theodorakis, E. A. “ANCA: A Family of Fluorescent Probes that Bind and Stain Amyloid Plaques in Human Tissue” ACS Chem. Neurosci. 2011, 2, 249-255. PDF File Supplement PDF

109. Dakanali, M.; Theodorakis, E. A. “Polyprenylated Phloroglucinols and Xanthones” in Biomimetic Organic Synthesis, Poupon, E., Nay, B. (Eds.), 2011, Wiley-VCH Verlag GmbH & Co. KgaA, Weinheim, Germany.  doi: 10.1002/9783527634606.ch12. PDF File

110. Nguyen, T. X.; Dakanali, M. Trzoss, L.; Theodorakis, E. A. “Enantioselective Synthesis of the ABC ring motif of Norzoanthamine Based on Asymmetric Robinson Annulation Reactions” Org. Lett. 2011, 13, 3308-3311. PDF File Supplement PDF

111. Fischer, D.; Nguyen, T. X.; Trzoss, L.; Dakanali, M.; Theodorakis, E. A. “Intramolecular cyclization strategies toward the synthesis of zoanthamine alkaloids” Tetrahedron Lett. 2011, 52, 4920-4923. PDF File Supplement PDF

112. Trzoss, L.; Xu, J.; Lacoske, M. H.; Mobley, W. C.; Theodorakis, E. A. “Enantioselective Total Synthesis of (–)-Jiadifenin, a Potent Neurotrophic Modulator” Org. Lett. 2011, 13, 4554-4557. PDF File Supplement PDF

113. Saitman, A.; Rulliere, P.; Sullivan, S. D. E.; Theodorakis, E. A. “Total synthesis of norcembrenolide B and scabrolide D” Org. Lett. 2011, 13, 5854-5857. PDF File Supplement PDF

114. Howell, S.; Dakanali, M.; Theodorakis, E. A.; Haidekker, M. A. “Intrinsic and extrinsic temperature-dependency of viscosity-sensitive fluorescent molecular rotors” J. Fluoresc. 2012, 22, 457-465. PDF File

115. Xu, J.; Caro-Diaz, E. J. E.; Batova, A.; Sullivan, S. D. E.; Theodorakis, E. A. “Formal Synthesis of (–)-Englerin A and Cytotoxicity Studies of Truncated Englerins” Chemistry, Asian J. 2012, 7, 1052-1060.
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116. Guizzunti, G.; Batova, A.; Chantarasriwong, O.; Dakanali, M.; Theodorakis, E. A. “Subcellular localization and activity of gambogic acid” ChemBioChem 2012, 13, 1191-1198. PDF File
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117. Xu, J.; Caro-Diaz, E. J. E.; Trzoss, L.; Theodorakis, E. A. “Nature-Inspired Total Synthesis of (–)-Fusarisetin A” J. Am. Chem. Soc. 2012, 134, 5072-5075. PDF File Supplement PDF
Highlighted in C&En News

118. Guizzunti, G.; Theodorakis, E. A.; Yu, A. L.; Zurzolo, C.; Batova, A. “Cluvenone induces apoptosis via a direct target in mitochondria: A possible mechanism to circumvent chemo-resistance?” Invest. New Drugs 2012, 30, 1841-1848. PDF File

119. Dakanali, M.; Do, T. H.; Horn, A.; Chongchivivat, A.; Jarusreni, T.; Lichlyter, D.; Guizzunti, G.; haidekker, M. A.; Theodorakis, E. A. “Self-calibrating viscosity probes: Design and subcellular localization” Bioorg. & Med. Chem. Lett. 2012, 20, 4443-4450. PDF File Supplement PDF

120. Xu, J.; Caro-Diaz, E. J. E.; Lacoske, M. H.; Hung, C.-I.; Jamora, C.; Theodorakis, E. A. “Fusarisetin A: scalable total synthesis and related studies” Chem. Sci. 2012, 3, 3378-3386. PDF File Supplement PDF

121. Cao, K.; Farahi, M.; Dakanali, M.; Chang, W. M.; Sigurdson, C. J.; Theodorakis, E. A.; Yang, J. “ANCA probes fluorescently discriminate between amyloid-b and prion plaques in brain” J. Am. Chem. Soc. 2012, 134, 17338-17341. PDF File Supplement PDF
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122.  Martinez-Montero, S.; Fernandez, S.; Sanghvi, Y. S.; Theodorakis, E. A.; Detorio, M. A.; Mcbrayer, T. R.; Whitaker, T.; Schinazi, R. F.; Gotor, V.; Ferrero, M. “Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2’,3’-dideoxy-2’,2’-difluoro-4’-azanucleosides” Bioorg. & Med. Chem. 2012, 20, 6885-6893. PDF File Supplement PDF

123. Trzoss, L.; Xu, J.; Lacoske, M. H.; Mobley, W. C.; Theodorakis, E. A. “Illicium Sesquiterpenes: Divergent Synthetic Strategy and Neurotrophic Activity Studies” Chemistry-Eur. J. 2013, 19, 6398-6408. PDF File Supplement PDF

124. Saitman, A.; Sullivan, S. D. E.; Theodorakis, E. A. “A strategy toward the synthesis of C13-oxidized cembrenolides” Tetrahedron Lett. 2013, 54, 1612-1615. PDF File Supplement PDF

125. Elbel, K. M.; Guizzunti, G.; Theodorakis, M. A.; Xu, Jing, Batova, A.; Dakanali, M.; Theodorakis, E. A. “A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthones” Org. Biomol. Chem. 2013, 11, 3341-3348. PDF File Supplement PDF

126. Saitman, A.; Theodorakis, E. A. “Synthesis of a highly functionalized core of verrillin” Org. Lett. 2013, 15, 2410-2413. PDF File Supplement PDF

127. Trzoss, L.; Xu, J.; Lacoske, M. H.; Theodorakis, E. A. “Synthesis of the tetracyclic core of Illicium sesquiterpenes using an organocatalyzed asymmetric Robinson annulation” Beilstein J. Org. Chem. 2013, 9, 1135-1140. PDF File Supplement PDF

128. Papakyriakou, A.; Zervoudi, E.; Theodorakis, E. A.; Saveanu, L.; Stratikos, E.; Vourloumis, D. “Novel selective inhibitors of aminopeptidases that generate antigenic peptides” Bioorg. & Med. Chem. Lett. 2013, 13, 4832-4836. PDF File Supplement PDF

129. Williams, R. T.; Yu, A. L.; Diccianni, M. B.; Theodorakis, E. A.; Batova, A. “Englerin A induces multiple mechanisms of cell death and autophagy” J. Exper. & Clin. Cancer Res. 2013, 32, 57. PDF File

130. Xu, J.; Lacoske, M. H.; Theodorakis, E. A. “Neurotrophic natural products: Chemistry and biology” Angew. Chem. Int. Ed. 2014, 53, 956-987. PDF File


 
   
     
 
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