how to create your own website

PUBLICATIONS & Patents

2014-2010

137"Anti-inflammatory Actions of Acanthoic Acid-Related Diterpenes Involve Activation of the PI3K p110g/d Subunits and Inhibition of NF-kB" Traves, Paqui, G.; Pimentel-Santillana, Maria; Rico, Daniel; Rodriguez, Nuria; Miethke, Thomas; Castrillo, Antonio; Theodorakis, Emmauel A.; Martin-Sanz, Paloma; Palladino, Michael A.; Bosca, Lisardo, Chem Biol., 2014, 21(8), 955-66.

136. "Fusarisetins: structure–function studies on a novel class of cell migration inhibitors" Caro-Diaz, Eduardo J.E.; Aung, Aereas; Varghese, Shyni; Theodorakis, Emmanuel A. Org Chem Front., 2014, 1(2), 135–139.

135. "Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling" Shih, Yu-Ru V.; Hwang, YongSung; Phadke, Ameya; Kang, Heemin; Hwang, Nathaniel S.; Caro, Eduardo J.; Nguyen, Steven; Siu, Michael; Theodorakis, Emmanuel A.; Gianneschi, Nathan C.; Vecchio, Kenneth S.; Chien, Shu; Lee, Oscar K.; Varghese, Shyni, PNAS, 2014, 111(3), 990-995

134. "Neurotrophic Natural Products: Chemistry and Biology" Xu, Jing; Lacoske, Michelle H.; Theodorakis, Emmanuel A., Angew Chem. Int. Ed. Engl., 2014, 53(4), 956-987

133. "Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy" Williams, Richard T.; Yu, Alice L.; Diccianni, Mitchell B.; Theodorakis, Emmanuel A.; Batova, Ayse, Journal of Experimental & Clinical Cancer Research, 2013, 32(57)

132. "Novel selective inhibitors of aminopeptidases that generate antigenic peptides" Theodorakis, Emmanuel A.; Saveanu, Loredana; Stratikos, Efstratios; Vourloumis, Dionisios. Bioorganic & Medicinal Chemistry Letters, 2013, 23(17), 4832-4836.

131. "A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthones" Elbel, K. M.; Guizzunti, G.; Theodorakis, M. A.; Xu, Jing, Batova, A.; Dakanali, M.; Theodorakis, E. A. Organic & biomolecular chemistry, 2013, 11(20), 3341-3348.

130. "A strategy toward the synthesis of C13-oxidized cembrenolides" Saitman, A.; Sullivan, S. D. E.; Theodorakis, E. A. Tetrahedron letters, 2013, 54(12), 1612-1615.

129. "Synthesis of a highly functionalized core of verrillin" Saitman, A.; Theodorakis, E. A. Organic letters, 2013, 15(10), 2410-2413.

128. "Synthesis of the tetracyclic core of Illicium sesquiterpenes using an organocatalyzed asymmetric Robinson annulation" Trzoss, L.; Xu, J.; Lacoske, M. H.; Theodorakis, E. A. Beilstein journal of organic chemistry, 2013, 9(1), 1135-1140.

127. "Illicium Sesquiterpenes: Divergent Synthetic Strategy and Neurotrophic Activity Studies" Trzoss, L.; Xu, J.; Lacoske, M. H.; Mobley, W. C.; Theodorakis, E. A. Chemistry–A European Journal, 2013, 19 (20), 6398-6408.

126. "Fusarisetin A: scalable total synthesis and related studies" Xu, J.; Caro-Diaz, E. J. E.; Lacoske, M. H.; Hung, C.-I.; Jamora, C.; Theodorakis, E. A. Chemical science, 2012, 3 (12), 3378-3386.

125. "Formal Synthesis of (−)‐Englerin A and Cytotoxicity Studies of Truncated Englerins" Xu, J.; Caro-Diaz, E. J. E.; Batova, A.; Sullivan, S. D. E.; Theodorakis, E. A. Chemistry–An Asian Journal, 2012, 7 (5), 1052-1060.

124. "Nature-inspired total synthesis of (−)-fusarisetin A" Xu, J.; Caro-Diaz, E. J. E.; Trzoss, L.; Theodorakis, E. A. JACS, 2012, 134 (11), 5072-5075.

123. "Subcellular localization and activity of gambogic acid" Guizzunti, G.; Batova, A.; Chantarasriwong, O.; Dakanali, M.; Theodorakis, E. A. ChemBioChem, 2012, 13 (8), 1191-1198

122. "Aminonaphthalene 2-cyanoacrylate (ANCA) probes fluorescently discriminate between amyloid-β and prion plaques in brain" Cao, K.; Farahi, M.; Dakanali, M.; Chang, W. M.; Sigurdson, C. J.; Theodorakis, E. A.; Yang, J. JACS, 2012, 134 (42), 17338-17341

121. "Self-calibrating viscosity probes: design and subcellular localization" Dakanali, M.; Do, T. H.; Horn, A.; Chongchivivat, A.; Jarusreni, T.; Lichlyter, D.; Guizzunti, G.; Haidekker, M. A.; Theodorakis, E. A. Bioorganic & medicinal chemistry, 2012, 20 (14), 4443-4450

120. "Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2′, 3′-dideoxy-2′, 2′-difluoro-4′-azanucleosides" Martinez-Montero, S.; Fernandez, S.; Sanghvi, Y. S.; Theodorakis, E. A.; Detorio, M. A.; Mcbrayer, T. R.; Whitaker, T.; Schinazi, R. F.; Gotor, V.; Ferrero, M. Bioorganic & medicinal chemistry, 2012, 20 (23), 6885-6893

119. “ANCA probes fluorescently discriminate between amyloid-b and prion plaques in brain” Cao, K.; Farahi, M.; Dakanali, M.; Chang, W. M.; Sigurdson, C. J.; Theodorakis, E. A.; Yang, J. J. Am. Chem. Soc. 2012, 134, 17338-17341.

118. "Intrinsic and extrinsic temperature-dependency of viscosity-sensitive fluorescent molecular rotors" Howell, S.; Dakanali, M.; Theodorakis, E. A.; Haidekker, M. A. Journal of fluorescence, 2012, 22 (1), 457-465

117. "Cluvenone induces apoptosis via a direct target in mitochondria: a possible mechanism to circumvent chemo-resistance?" Guizzunti, G.; Theodorakis, E. A.; Yu, A. L.; Zurzolo, C.; Batova, A. Investigational new drugs, 2012, 30(5), 1841-1848

116. "Total synthesis of Norcembrenolide B and Scabrolide D" Saitman, A.; Rulliere, P.; Sullivan, S. D. E.; Theodorakis, E. A. Organic letters, 2011, 13 (21), 5854-5857

115. "Synthesis and evaluation of self-calibrating ratiometric viscosity sensors" Yoon, H.-J.; Dakanali, M.; Lichlyter, D.; Chang, W. M.; Nguyen, K. A.; Nipper, M. E. Haidekker, M. A.; Theodorakis, E. A. Organic & biomolecular chemistry, 2011, 9 (9), 3530-3540

114. "Enantioselective Synthesis of the ABC Ring Motif of Norzoanthamine Based on Asymmetric Robinson Annulation Reactions" Nguyen, T. X.; Dakanali, M. Trzoss, L.; Theodorakis, E. A. Organic letters, 2011, 13 (13), 3308-3311

113. "Intramolecular cyclization strategies toward the synthesis of zoanthamine alkaloids" Fischer, D.; Nguyen, T. X.; Trzoss, L.; Dakanali, M.; Theodorakis, E. A. Tetrahedron letters, 2011, 52 (38), 4920-4923

112. "ANCA: a family of fluorescent probes that bind and stain amyloid plaques in human tissue" Chang, W. M.; Dakanali, M.; Capule, C. C.; Sigurdson, C. J.; Yang, J.; Theodorakis, E. A. ACS chemical neuroscience, 2011, 2 (5), 249-255

111. “Polyprenylated Phloroglucinols and Xanthones" in Biomimetic Organic Synthesis, Poupon, E., Nay, B. (Eds.), Dakanali, M.; Theodorakis, E. A. 2011, Wiley-VCH Verlag GmbH & Co. KgaA, Weinheim, Germany. doi: 10.1002/9783527634606.ch12.

110. "Enantioselective Total Synthesis of (−)‐Jiadifenolide" Trzoss, L.; Xu, J.; Lacoske, M. H.; Mobley, W. C.; Theodorakis, E. A. Angewandte Chemie International Edition, 2011, 50 (16), 3672-3676

109. "Enantioselective synthesis of (−)-jiadifenin, a potent neurotrophic modulator" Trzoss, L.; Xu, J.; Lacoske, M. H.; Mobley, W. C.; Theodorakis, E. A. Organic letters, 2011, 13 (17), 4554-4557

108. "Detection of liposome membrane viscosity perturbations with ratiometric molecular rotors" Nipper, M. E.; Dakanali, M.; Theodorakis, E. A.; Haidekker, M. A. Biochimie, 2011, 93 (6), 988-994

107. "Synthesis of (−)-callicarpenal, a potent arthropod repellent" Ling, T.; Xu, J.; Smith, R.; Ali, A.; Cantrell, C. L. Theodorakis, E. A. Tetrahedron, 2011, 67 (17), 3023-3029

106. "Dyes with segmental mobility: molecular rotors" Haidekker, M. A.; Nipper, M.; Mustafic, A.; Lichlyter, D.; Dakanali, M.; Theodorakis, E. A. Advanced Fluorescence Reporters in Chemistry and Biology I, 2010, 267-308

105. "Chemical biology studies on norrisolide" Guizzunti, G.; Brady, T. P.; Fischer, D.; Malhotra, V.; Theodorakis, E. A. Bioorganic & medicinal chemistry, 2010, 18 (6), 2115-2122

104. "Molecular rotors: synthesis and evaluation as viscosity sensors" Sutharsan, J.; Lichlyter, D.; Wright, N. E.; Dakanali, M.; Haidekker, M. A.; Theodorakis, E. A. Tetrahedron, 2010, 66 (14), 2582-2588

103. "Environment-sensitive behavior of fluorescent molecular rotors" Haidekker, M. A.; Theodorakis, E. A. Journal of biological engineering, 2010, 4 (1), 11

102. "Enantioselective formal synthesis of (−)-englerin A via a Rh-catalyzed [4+ 3] cycloaddition reaction" Xu, J.; Caro-Diaz, E. J. E.; Theodorakis, E. A. Organic letters, 2010, 12 (16), 3708-3711

101. "Imaging of flow patterns with fluorescent molecular rotors" Mustafic, A.; Huang, H.-M.; Theodorakis, E. A. Haidekker, M. A. Journal of fluorescence, 2010, 20 (5), 1087-1098

100. "The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity" Batova, A.; Altomare, D.; Chantarasriwong, O.; Ohlsen, K.L.; Creek, K.E.; Lin, Y.; Messersmith, A.; Yu, A.L.; Yu, J.; Theodorakis, E.A. Molecular cancer therapeutics, 2010, 9 (11), 2869-2878

99. "Chemistry and Biology of the Caged Garcinia Xanthones" Chantarasiwong, O.; Batova, A.; Chavasiri, W.; Theodorakis, E.A. Chemistry–A European Journal, 2010, 16 (33), 9944-9962