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PUBLICATIONS & Patents

2004-2000

68. "Fragmentation of Golgi Membranes by Norrisolide and Designed Analogues" Brady, T. P.; Wallace, E. K.; Kim, S. H.; Guizunnti, G.; Malhotra, V.; Theodorakis, E. A. Bioorg. & Med. Chem. Lett. 2004, 14, 5035-5039.

67. "Unified Synthesis of Caged Garcinia Natural Products Based on a Site-Selective Claisen/Diels-Alder/Claisen Rearrangement"  Tisdale, E. J.; Slobodov, I; Theodorakis, E. A.Proc. Nat. Acad. Sci. USA 2004, 101, 12030-12035.

66. "Stereoselective Total Synthesis of (-)-Borrelidin" Vong, B. G.; Kim, S. H.; Abraham, S.; Theodorakis, E. A. Angew. Chem. Int. Ed. 2004, 43, 3947-3951.

65. "Quinone Sesquiterpenes: A Challenge for the Development of a New Synthetic Methodology" GLacoske, Theodorakis, E. A.; Ling, T.; Rueden, E. J.; Poupon E.; Kim S. H. Strategies and Tactics in Organic Synthesis, 2004, Vol. 5, 111-131. 

64. "Synthesis of (+)- and (-)-Isocarvone" Gonzalez, M. A.; Ghosh, S.; Rivas, F.; Fischer, D.; Theodorakis, E. A. Tetrahedron Lett. 2004, 45, 5039-5041.

63. "Hydrophilic Molecular Rotor Derivatives: Synthesis and Characterization" Haidekker, M. A.; Brady, T. P.; Chalian, S. H.; Akers, W.; Lichlyter, D.; Theodorakis, E. A. Bioorg. Chem. 2004, 32, 274-289.

62. "3,3'-Oxybis(Dimethoxytrityl Chloride) (O-DMT): Synthesis and Applications of a Novel Bifunctional Protecting Group" Oka, N.; Sanghvi, Y. S.; Theodorakis, E. A. Bioorg. & Med. Chem. 2004, 14, 3241-3244.

61. "Synthesis and in vitro Antitumour Activity of Phthalimide-Based Polymers Containing Camptothecin" Lee, N.-J.; Lee, S.-J.; Kim, S.-H.; Soo, K.-Y.; Moon, S.-B.; Kang, K.-T.; Theodorakis, E. A. Eur. Polymer J. 2004, 40, 1291-1296.

60. "Stereoselective Synthesis of the ABC Ring System of Norzoanthamine" Ghosh, S.; Rivas, F.; Fischer, D.; Gonzalez, M. A. Org. Lett. 2004, 6, 941-944.

59. "Synthesis of Fused Tetrahydrofuran-y-lactone Motifs via a One-Pot Ring Expansion of Cyclopropane Rings" Kim, C.; Brady, T.; Kim, S.; Theodorakis, E. A.  Synth. Commun. 2004, 34, 1951-1965.

58. "1,2-Ethylene-3,3-Bis(4'-4"-Dimethoxytrityl Chloride) (E-DMT): Synthesis and Applications of a Novel Protecting Reagent"  Oka, N.; Sanghvi, Y. S.; Theodorakis, E. A. Synlett 2004, 5, 823-826.

57. "Stereoselective Total Synthesis of (+)-Norrisolide" Brady, T.; Kim, S.; Wen, K.; Theodorakis, E. A. Angew. Chem. Int. Ed. 2004, 43, 739-742.

56. "Biomimetic Total Synthesis of Forbesione and Desoxymorellin Utilizing a Tandem Claisen/Diels-Alder/Claisen Rearrangement" Tisdale, E. J.; Slobodov, I; Theodorakis, E. A. Org. Biomol. Chem. 2003, 1, 4418-4422.

55. "MDPSCl2: A New Protecting Group for Chemoselective Synthesis of 2'-O-Alkylated Guanosines" Chow, S.; Wen, K.; Sanghvi, Y. S.; Theodorakis, E. A. Nucleos. Nucleot. Nucl. Acids 2003, 22, 583-587.

54. "Anti TNF-alpha Therapies: The Next Generation" Palladino, M. A.; Bahjat, F. R.; Theodorakis, E. A.; Moldawer, L. L. Nature Reviews Drug Discovery 2003, 2, 736-746

53. "Synthesis of a Novel Family of Diterpenes and their Evaluation as Anti-inflammatory Agents" Lam, T.; Ling, T.; Chowdhury, C.; Chao, T.-H.; Bahjat, F. R.; Lloyd, G. K.; Moldawer, L. L.; Palladino, M. A.; Theodorakis, E. A. Bioorg. & Med. Chem. Lett. 2003, 13, 3217-3221.

52. "Total Synthesis of Seco-lateriflorone" Tisdale, E. J.; Vong, B. G.; Li, H.; Kim, S. H.; Chowdhury, C.; Theodorakis, E. A. Tetrahedron 2003, 59, 6873-6887.

51. "Synthesis and Antitumor Activity of Medium Molecular Weight Phthalimide-Polymers of Camptothecin" Lee, N.-J.; Ju, S.-S.; Cho, W.-J.; Kim, S. H.; Kang, K.-T.; Brady, T.; Theodorakis, E. A. Polym. Int. 2003, 52, 1339-1345.

50. "Synthetic Studies on Borrelidin; Enantioselective Synthesis of the C1-C12 Fragment" Vong, B. G.; Abraham, S.; Xiang, A. X.; Theodorakis, E. A. Org. Lett. 2003, 5, 1617-1620.

49. "Regioselective Synthesis of the Tricyclic Core of Lateriflorone" Tisdale, E. J.; Li, H.; Vong, B. G.; Kim, S. H.; Theodorakis, E. A. Org. Lett. 2003, 5, 1491-1494.

48. "Novel Synthesis of 2'-O-Methylguanosine" Chow, S.; Wen, K.; Sanghvi, Y. S.; Theodorakis, E. A. Bioorg. & Med. Chem. Lett. 2003, 13, 1631-1634. 

47. "Total Synthesis of Atroviridin" Tisdale, E. J.; Kochman, D. A.; Theodorakis, E. A. Tetrahedron Lett. 2003, 44, 3281-3284.

46. "Synthesis and Antitumor Activity of Phthalimide-Based Polymers Containing Camptothecin" Lee, N.-J.; Theodorakis, E. A. Macromol. Res. 2003, 11, 47-52. 

45. "Synthesis and Antitumor Activity of Medium MolecularWeight Phthalimide-Polymers of Camptothecin" Lee, N.-J.; Ju, S.-S.; Cho, W.-J.; Kim, S. H.; Kang, K.-T.; Brady, T.;Theodorakis, E. A. Eur. Polymer J. 2003, 39, 367-374.

44. "Stereoselective Synthesis of the Fully Functionalized Core Fragment of Terpentecin" Ling, T.; Rivas, F.; Theodorakis, E. A. Tetrahedron Lett. 2002, 43, 9019-9022.

43. "Unified Synthesis of Quinone Sesquiterpenes Based on a Radical Decarboxylation and Quinone Addition Reaction" Ling, T.; Poupon, E.; Rueden, E. J.; Theodorakis, E. A. J. Am. Chem. Soc. 2002, 124, 12261-12267.

42. "Synthesis of 2'-O-Methoxyethyl-Guanosine Using a Novel Silicon-Based Protecting Group" Wen, K.; Chow, S.; Sanghvi, Y. S.; Theodorakis, E. A. J. Org. Chem. 2002, 67. 7887-7889.

41. "Phospholipid-bound Molecular Rotors: Synthesis and Characterization" Haidekker, M. A.; Brady, T.; Wen, K.; Okada, C.; Stevens, H. Y.; Snell, J. M.; Frangos, J. A.; Theodorakis, E. A. Bioorg. & Med. Chem. 2002,10, 3627-3636.

40. "Regioselective Synthesis of the Bridged Tricyclic Core of Garcinia Natural Products via Intramolecular Aryl Acrylate Cycloadditions" Tisdale, E. J.; Chowdhury, C.; Vong, B. G.; Li, H.; Theodorakis, E. A. Org. Lett. 2002, 4, 909-912.

39. "Synthesis of (-) llimaquinone via a Radical Decarboxylation and Quinone Addition Reaction" Ling, T.; Poupon, E.; Rueden, E. J.; Theodorakis, E. A. Org. Lett. 2002, 4, 819-822.

38. "A Novel Approach to Blood Plasma Viscosity Measurement Using Fluorescent Molecular Rotors" Haidekker, M. A.; Tsai, A. G.; Brady, T.; Stevens, H. Y.; Frangos, J. A.; Theodorakis, E. A. Amer. J. Physiol. Heart Circ. Physiol. 2002, 282, H1609-H1614.

37. "Syntheses and Biological Activities of New Phthalimide-based Polymers Containing 5-Fluorouracil" Lee, N.-J.; Koo, J.-C.; Ju, S.-S.; Moon, S.-B.; Cho, W.-J.; Jeong, I.-C.; Lee, S.-J.; Cho, M.-Y.; Theodorakis, E. A. Polym. Int. 2002, 51, 569-576.

36. "Enantioselective Synthesis of the Anti-inflammatory Agent (-)-Acanthoic Acid" Ling, T.; Chowdhury, C.; Kramer, B. A.; Vong, B. G.; Palladino, M. A.; Theodorakis, E. A. J. Org. Chem. 2001, 66, 8843-8853.

35. "Syntheses and Biological Activities of Medium Molecular Weights Polymers Containing Exo-3, 6-epoxy-1,2,3,6-tetrahydrophthalimidocaproic Acid" Lee, N.-J.; Kang, N.-I.; Cho, W..-J; Kim, S.-H.; Kang, K.-T.; Theodorakis, E. A. Polym. Int. 2001, 50, 1010-1015.

34. "New Fluorescent Probes for the Measurement of Cell Membrane Viscosity" Haidekker, M. A.; Ling, T.; Anglo, M.; Stevens, H.Y.; Frangos, J. A.; Theodorakis, E. A. Chemistry & Biology 2001, 8, 123-131.

33. "Investigation of the Biological Mode of Action of Clerocidin Using Whole Cell Assays" Jamora, C.; Theodoraki, M.; Malhotra, V.; Theodorakis, E. A. Bioorg. & Med. Chem. 2001, 9, 1365-1370.

32. "Stereoselective Synthesis of (-) -Acanthoic Acid" Ling, T.; Kramer, B. A.; Palladino M. A.; Theodorakis, E. A. Organic Lett. 2000, 2, 2073-2076.

31. "Efficient Synthesis of the C1-C8 Fragment of Reveromycins"  Drouet, K. E.; Tran, H. V.; Theodorakis, E. A. Synthetic Commun. 2000, 30, 3617-3628

30. "Enantioselective Synthesis of the [6,6] Spiroketal Core of Reveromycin A" Drouet, K. E.; Ling, T.; Tran, H. V.; Theodorakis, E. A. Organic Lett. 2000, 2, 207-210.

29. "Stereoselective Total Synthesis of Reveromycin B and C19-epi -Reveromycin B" Drouet, K. E.; Theodorakis, E. A. Chemistry-A European J. 2000, 6, 1987-2001.